Kinkade HYDE STREET AND THE BAY SAN FRANCISCO

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the first few dozen individual cells. When it comes to vertebrates, though, scientists only had, at best, a partial view of what comes next. This year, researchers from Germany created a specialized microscope and observed the formation and known for over 400 years that there are two types of fat: white and brown. Brown fat cells have a much higher concentration of mitochondria and burn energy for heat; white fat cells are what many of us readily see in our midsection. Both types of fat cells were assumed to be related and come from the same progenitor cell type. Using the observation that the gene PRDM16 spurs specialization of brown fat, US researchers expected that if they blocked PRDM16 activity, the brown fat precursor cells would become white fat cells. They growth of a zebrafish embryo. They watched it from a single cell until it reached a cluster of almost 16,000 individual cells. The movies are freely available on the Internet, and well worth watching. * Color Coded Fat: It has been